CELL & TISSUE CULTURE
COLLAGEN AS UNIVERSAL MATRIX IN CELL & TISSUE CULTURE
Due to its central role as an extracellular matrix protein in cell adhesion and organ formation, collagen is an ideal substrate for cell culture and tissue engineering. Using an advanced technology for collagen purification and processing, our unique fibrous collagen retains the in vivo-like structure of insoluble collagen fibers with excellent proven biocompatibility and biodegradability.
All our collagen products provide natural signals for better attachment, growth, and differentiation, thereby supporting authentic cell performance and complex tissue formation. They are suited for a wide range of biomedical research and development applications that based on cell & tissue cultures
Collagen type I is a major structural component of the extracellular matrix
where it forms a fibrillar scaffold for cell adhesion and the formation of connective tissues.
Collagen scaffolds for 2D & 3D cultures
Stable & flexible films for optimal culture performance
Our permeable Collagen Films are universal scaffolds for the culture of adherent cells.
- Use for general cell biology research
- Wide range of applications in regenerative medicine
- Cells are seeded on top, non-porous membranes facilitate co-cultures
- Membrane-culture complex can be transferred for multi-purpose use
- Histological analysis can be performed using standard protocols
- Metabolic activity can be monitored using colorimetric methods
- Freezing & thawing doesn’t affect features
Collagen membranes as tissue carriers
The mechanical characteristics and the biocompatibility of our collagen membranes facilitate the establishment of co-cultures and the engineering of thin transferable tissue constructs.
- Our collagen membranes can be used to generate 3D tissue models, e.g., skin, or organ-on-chip models, e.g., intestinal barrier.
- All membranes are widely applicable, including tissue engineering or regenerative medicine
- Validated, established products
The following primary cells have been tested on our collagen membranes:
Heart & vascular system
Heart & vascular system
- Neonatal cardiac fibroblasts
- Embryonic cardiomyocytes
- Neonatal cardiomyocytes
- Cardiomyocytes
- Embr. ventricular myocytes
- Card. microvasc. endot. cells
Eyes
Eyes
- Cornea endothelial cells
- Cornea epithelial cells
- Iris pigment epithelial cells
- Retinal pigment epithelial cells
Bone & Cartilage
Bone & Cartilage
- Osteoblast from adipose MSCs
- Chondrocytes
- Chondrocytes from adipose MSCs
- Meniscus cells
Nervous system
Nervous system
- Astrocytes
- Fetal dopamine neuronal cells
- Fetal neocortical neuronal cells
- Dorsal root ganglion neur. cells
- Enteric neuronal cells
Liver & Pancreas
Liver & Pancreas
- Hepatocytes
- Pancreatic cells
Skin
Skin
- Keratinocytes
- Epidermal keratinocytes (hEKs)
- Melanocytes from hair follicle
Urogenital tract
Urogenital tract
- Urothelial cells
Stem cells
Stem cells
- Nucleus pulposus (NP) cells
- Dental pulp pluripotent-like stem cells (DPPSC)
- Mesenchymal stem cells (different tissues)
