ADVANCED THERAPY MEDICINAL PRODUCTS (ATMPs)
“Breaking new grounds in regenerative medicine”
ADVANCED THERAPY MEDICINAL PRODUCTS (ATMPs)
Breaking new grounds in regenerative medicine
The vision of regenerative medicine is to replace or repair tissues, damaged by disease, injury, or age as an alternative to conventional drug or physical therapy. Advanced therapy medicinal products (ATMPs) based on stem cells or tissues offer groundbreaking new opportunities for tissue regeneration.
Based on the Collagen Cell Carrier®, Viscofan BioEngineering has developed a thin collagen membrane for implantology as a combined ATMP. The biocompatible, suturable scaffold can carry therapeutic cells or provide a natural matrix for the cellular recolonization of severely damaged tissues.
Our goal is to develop novel therapies in cardiology, urology, dermatology and dentistry based on our collagen I based membranes together with academic and clinical partners.
Pipeline
Novel therapy for cardiac insufficiency – a collaborative clinical development
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PROJECT
Development of a regenerative therapy for cardiac insufficiency in collaboration with the University Clinic of Navarra. -
APPLICATION
Generation of a cell matrix complex of adipose-derived stem cells (ADSCs) seeded on a collagen membrane. Transplantation to the site of heart tissue damage. -
OUTCOME
Significant enhancement of cell retention at the implantation site and consistent improvement of tissue function in preclinical and a clinical phase-I study. -
CONCLUSION
The stem cell collagen membrane complex offers an opportunity for a new therapy for cardiac insufficiency
REFERENCES
Arana M et al., 2013; Arana M et al., 2014; Valarmathi et al. 2018; Lopez-Diaz de Cerio A et al., 2021
